The UNC-53-mediated Interactome: Analysis of its Role in the Generation of the C. elegans Connectome

This book gives an overview of various interactomes involved in dorsal ventral (DV) and anterior posterior (AP) guidance, their mechanisms of action, subcellular localizations, and functional roles. It will provide readers a better understanding of the development of the nervous system, which in turn will help to find cures to various neural and other disorders.​

In nematodes there are two types of guidance systems, including DV and AP guidance. The signaling process that guides the growth c...