Pharmaceutical Biotechnology: Fundamentals and Applications

Overview

Completely revised text that reflects to emergent trends and cutting-edge advances in pharmaceutical biotechnology, this Third Edition provides a well-balanced framework for understanding every major aspect of pharmaceutical biotechnology, including drug development, production, dosage forms, administration, and therapeutic developments. New chapters cover evolving areas regarding biopharmaceuticals, including oligonucleotides, siRNA and various monoclonal antibodies, immunogenicity, gene therapy, and the ...
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Overview

Completely revised text that reflects to emergent trends and cutting-edge advances in pharmaceutical biotechnology, this Third Edition provides a well-balanced framework for understanding every major aspect of pharmaceutical biotechnology, including drug development, production, dosage forms, administration, and therapeutic developments. New chapters cover evolving areas regarding biopharmaceuticals, including oligonucleotides, siRNA and various monoclonal antibodies, immunogenicity, gene therapy, and the regulatory issues factoring into the biopharmaceutical approval process
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Editorial Reviews

Doody's Review Service
Reviewer: David B Lebo, R.Ph., Ph.D.(Temple University School of Pharmacy)
Description: In this summary of pharmaceutical biotechnology, each chapter is written by an expert author on a specific area of biotechnology. This could lead to some inconsistencies among authors, but the organization of the book eliminates this problem.
Purpose: The purpose is to provide a complete overview of biotechnology to people with pharmacy backgrounds. The book does a great job meeting the objectives.
Audience: Some chapters are appropriate for pharmacy students and others are best for graduate students. However, the book would be fine for pharmacy students if accompanied by lectures to explain some concepts, and it would be good for graduate students if additional material is provided during lectures.
Features: The book is well organized and reader friendly. It presents the material by grouping the concepts into three sections: background science, therapeutic classes, and regulatory and economic considerations. I like the layout and the illustrations are wonderful.
Assessment: We use this book in our graduate program and I have not found a better text. The new edition is necessary because of the evolution of the science. A fourth edition will be needed in 3 to 5 years.
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Product Details

  • ISBN-13: 9781420067521
  • Publisher: Taylor & Francis
  • Publication date: 10/25/2007
  • Edition description: REV
  • Edition number: 3
  • Pages: 496
  • Product dimensions: 8.50 (w) x 11.00 (h) x 1.00 (d)

Table of Contents

Molecular Biotechnology. Biophysical and Biochemical Analysis of Recombinant Protein Structure and Analysis of Proteins. Production and Downstream Processing of Biotech Products. Formulation of Biotech Products, Including Biopharmaceutical Considerations. Pharmacokinetics and Pharmacodynamics of Peptide and Protein Drugs. Immunogenicity. Genomics, Proteomics and Additional Biotechnology-related Techniques. Gene Therapy. Oligonucleotides and siRNA. Hematopoetic Growth Factors. Interferons and Interleukins. Insulins. Growth Hormones. Recombinant Thrombolytics and Coagulation Factors. General Considerations of Monoclonal Antibodies. Monoclonal Antibodies in Oncology. Monoclonal Antibodies in Transplantation. Monoclonal Antibodies in Anti-inflammatory Therapy. Recombinant Human Deoxyribonuclease. Follicle-stimulating Hormone. Vaccines. Dispensing Biotechnology Products. Economic Considerations in Medical Biotechnology. Regulatory Issues and Drug Product Approval for Biopharmaceuticals
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