ADP-Ribosylation Reactions

ADP-Ribosylation Reactions

Paperback(Softcover reprint of the original 1st ed. 1992)

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Product Details

ISBN-13: 9781461264569
Publisher: Springer New York
Publication date: 11/09/2012
Edition description: Softcover reprint of the original 1st ed. 1992
Pages: 410
Product dimensions: 6.10(w) x 9.25(h) x 0.04(d)

Table of Contents

1: Molecular Biology.- Structure and Function of the Human Poly(ADP-Ribose) Polymerase.- Cloning of Poly(ADP-Ribose) Polymerase cDNA from Lower Eukaryotes.- Molecular Biology of Human Nuclear NAD+: ADP-Ribosyl-transferase (Polymerizing).- Strategies for Studying the Functions of PADPRP Genes on Human Chromosomes 1 and 13.- Expression of the DNA-Binding Domain of Human Poly(ADP-Ribose) Polymerase as a Trans-Dominant Inhibitor of Poly(ADP-Ribosyl)ation in Transfected Eucaryotic Cell Lines.- Directed Mutagenesis of Glutamic Acid 988 of Poly(ADP-Ribose) Polymerase.- Chicken Poly(ADP-Ribose) Polymerase. Complete Protein Sequence Deduced from cDNA, Comparison with Mammalian Enzyme Sequences.- Nuclear Poly(ADPR) Polymerase Expression and Activity in Rat Astrocytes Culture: Effects of bFGF.- Molecular Cloning of the Rat Poly(ADP-Ribose) Polymerase Gene and Preliminary Characterization of its Promoter and 5’-Flanking Regions.- Structure and Organization of the Mouse pADPRT Gene.- Strategies for Expressing Analogs of PADPRP in Eukaryotic Cells.- Expression and Characterization of PADPRP and a Novel Glucocorticoid-PADPRP “Finger Swapped” Protein from Escherichia coil.- Tumor Promoters, But Not EGF, Increase Nuclear Poly(ADP-Ribose) Polymerase Gene Expression in Rat Hepatocytes Initiated in Utero with DMN and Cultured After Birth in Low-Calcium Synthetic Medium.- Expression of the Gene for Poly(ADP-Ribose) Polymerase and DNA Polymerase ß in Rat Tissues and in Proliferating Cells.- Expression of Poly(ADP-Ribose) Polymerase in Differentiating HL-60 Cells..- 2: Cancer, DNA Repair, and Metabolism.- A Novel Model of Enzymatic Repair of U.V.-Induced DNA Damage in Human Cells.- Poly(ADP-Ribose) Polymerase in Xenopus Laevis.- ADP-Ribosylation is Involved in the Integration of Exogenous DNA into the Mammalian Cell Genome, but is not Required for the Episomal Replication or Expression of Autonomously Replicating Plasmids.- Inhibitors of Poly(ADP-Ribose) Polymerase Block the Infection of Mammalian Cells by Retroviral Vectors.- Detection and Analysis of NAD Binding Proteins Including Poly(ADP-Ribose) Polymerase Immobilized on the Membrane.- An In Vitro Replication System for Autonomously Replicating Mammalian Origin-Enriched Sequences.- Variation in Poly(ADP-Ribose) Polymerase Activity and 2’, 5’-Oligoadenylates Core Concentration in Estrogen-Stimulated Uterus and Liver of Immature and Adult Rats.- Possible Involvement of Poly(ADP-Ribose) Polymerase in the Brain Function.- Inhibition of Interferon-?-Dependent Induction of Major Histocompatibility Complex Class II Antigen by Expressing Exogenous Poly(ADP-Ribose) Synthetase Gene.- ADP-Ribose Polymers Bind Specifically and Non-covalently to Histones.- Poly(3’-deoxy ADP-ribosyl)ation of Proteins in Liver Chromatin Isolated from Rats Fed with Hepatocarcinogens.- ADP-Ribose Polymer Metabolism: Implications for Human Nutrition.- Some Aspects of Nuclear and Cytoplasmic ADP-ribosylation. Biological and Pharmacological Perspectives.- DNA Base Excision Repair Stimulates Poly(ADP-Ribose) Synthesis.- Studies on Poly(ADP-Ribosyl)ation in DNA Amplification and Mammalian Longevity.- DNA Topoisomerase I and Poly(ADP-Ribose) Polymerase in the Early Stages of Hepatocarcinogenesis.- Poly(ADP-Ribose) Polymerase Inhibitors Induce Murine Melanoma Cell Differentiation by a Mechanism Independent of Alterations in cAMP Levels and Protein Kinase A Activity.- Enhancement of Antimetabolite Cytoatoxicity by 3-Aminobenzamide in Chinese Hamster Ovary Cells is Independent of Poly(ADP-Ribose) Polymerase Inhibition.- Evidence for the Participation of Poly(ADP-Ribosyl)ation in Collagenase Gene Expression in Rabbit Synovial Fibroblasts after Treatment with Active Oxygen Released by Xantbin/Xanthinoxidase.- Enhancement of Oncogene-Mediated Transformation in Cloned Rat Embryo Fibroblast (CREF) Cells by 3-Anilnobenzamide.- Control of Procollagen Gene Transcription and Prolyl Hydroxylase Activity by Poly(ADP-Ribose).- Poly(ADP-Ribose) Synthesis in Lymphocytes of Systemic Lupus Erythematosus Patients.- Possible Involvement of Poly(ADP-Ribosyl)ation in Phenobarbital Promotion Activity in Rat Hepatocarcinogenesis.- 1-Methylnicotinamide Stimulates Cell Growth, Causes DNA Hypermethylation and Inhibits Induced Differentiation of Friend Erythroleukemia Cells.- 2-Aminobenzamide Antagonizes DNA De-methylation which Precedes Induced Differentiation of Friend Erythroleukemia Cells by N’-Methylnicotinamide.- ADP-Ribosylation of Rubisco in Lettuce Chloroplasts.- In Vivo Evidence in Humans of an Association Between ADP-Ribosylation Levels in Mononuclear Leukocytes and Immune Function.- Evaluation of the DNA Damage and Inhibition of DNA Repair Caused by the Benzamide Derivative Metoclopramide in Human Peripheral Mononuclear Leukocytes.- Nuclear ADP-Ribosyltranferase as Target Antigen in Chronic Graft-Versus-Host Disease.- Induction of Poly ADP-Ribosylation in Human Malignant Cells.- Proteolytic Cleavage of Poly(ADP-Ribose) Polymerase in Human Leukemia Cells Treated with Etoposide and Other Cytotoxic Agents.- ADP-Ribosylation of Topoisomerase II in Physiological Conditions.- Regulation of DNA Polymerase ß by Poly(ADP-Ribose) Polymerase.- Extensive Purification of Nuclear Poly(ADP-Ribose) Glycohydrolase.- Poly(ADP-Ribose) Polymerase and NMN Adenylyl-Transferase Interaction: Molecular and Immunological Studies.- Covalent Modification of Poly(ADP-Ribose) Polymerase by Reactive Benzamides.- Alterations in Repair of DNA Damage in Poly(ADP-Ribose) Polymerase Deficient Cell Lines.- 3: Enzymology.- Amino Acid Specific Modification of Poly(ADP-Ribose) Polymerase with Monomers and Polymers of ADP-Ribose.- Enzymatic Properties of Poly(ADP-Ribose) Polymerase and Poly(ADP-Ribose) Glycohydrolase on Chromatin.- A New “Transition-State” Inhibitor Specific for Poly(ADP-Ribose) Glycohydrolase.- Histones Affect Polymer Patterns Produced by Poly(ADP-Ribose) Polymerase.- Proteolytic Degradation of Poly(ADP-Ribose) Polymerase by Contaminating Proteases in Commercial Preparations of DNAse I.- Inactivation of the Polymerase but not the DNA Binding Function of ADPRT by Destabilization of one of its Zn2+ Coordination Centers by 6-Nitroso-1,2-Benzopyrone.- Conversion of Poly(ADP-Ribose) Polymerase Activity to NAD-Glycohydrolase During Retinoic Acid Induced Differentiation of HL60 Cells.- Improved Assays of Poly(ADP-Ribose) Metabolizing Enzymes.- Specific Inhibitors of Poly(ADP-Ribose) Synthetase.- Automodification and NADase Activity of Poly(ADP-Ribose) Polymerase.- The Poly(ADP-Ribose)-Protein Shuttle of Chromatin.- 4: Mono ADP-Ribosylation.- Endogenous Mono-ADP-Ribosylation of Wild-Type and Mutant Elongation Factor 2 in Eukaryotic Cells.- Heterogeneity of ADP-Ribosylation Reaction in Sulfolobus solfataricus.- A Novel C3-like ADP-Ribosyltransferase Produced by Clostridium limosum.- The 52 kDa ADP-Ribosylated Protein in the Rat Heart Plasma Membrane: Is it Gsa?.- Biochemical and Developmental Characterization of ADP-Ribosylation Factors A Family of 20 kDa Guanine Nucleotide-binding Proteins.- Nonenzymatic ADP-Ribosylation of Cysteine.- Molecular and Immunological Characterization of ADP-Ribosylarginine Hydrolases.- Characterization of the Family of Mammalian Genes Encoding ADP-Ribosylation Factors.- Purification and Characterisation of NAD: Arginine Mono ADP-Ribosyl Transferase from Chicken Erythrocytes; Identification of some Enzyme Inhibitors.- Target Proteins for Arginine Specific ADP-Ribosyltransferase in Chickens.- NAD+ Biosynthesis in Human Placenta: Characterization of Homogeneous NMN Adenylyltransferase.

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