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The two volume set LNCS 10072 and LNCS 10073 constitutes the refereed proceedings of the 12th International Symposium on Visual Computing, ISVC 2016, held in Las Vegas, NV, USA in December 2016.

The 102 revised full papers and 34 poster papers presented in this book were carefully reviewed and selected from 220 submissions. The papers are organized in topical sections: Part I (LNCS 10072) comprises computational bioimaging; computer graphics; motion and tracking; segmentation; pattern recog...