Animal Models of Parkinson´s Disease

Essay from the year 2003 in the subject Biology - Neurobiology, grade: 1,0 (Distinction), Oxford University (Department of Experimental Psychology), language: English, abstract: Parkinson’s disease (PD) was the first neurological disease to b e modelled in animals. Early models of PD used toxins which selectively targeted dopaminergic neurons, such as reserpine, 6 -hydroxydopamine, and 1 -methyl-4-phenyl-1,2,3,6tetrahydropyridine. These initial models have greatly contributed to the current...