Antipsychotics: History, Science, and Issues
The problem of serious mental illness is a widely discussed topic in the media and popular culture. This text provides a comprehensive analysis of antipsychotic medications, covering historical, social, and scientific viewpoints on this important and controversial class of medications.

Antipsychotics are unique drugs with the ability to alter how people think and communicate. As a result, physicians must weigh a range of implications when prescribing antipsychotics. Antipsychotics: History, Science, and Issues offers a robust explanation of antipsychotic medications that covers the historical, ethical, medical, legal, and scientific dimensions of antipsychotics.

The chapters explore topics ranging from the science of how examples of this class of drug actually work in the body to the social and legal implications of antipsychotics, making this subject understandable and relatable for lay readers who are not mental health practitioners. Readers will learn why prescribing antipsychotics is often a difficult decision due to the inherent risks of giving these medications to different types of patients and appreciate how mental health laws impact psychiatrists' prescribing practices.

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Antipsychotics: History, Science, and Issues
The problem of serious mental illness is a widely discussed topic in the media and popular culture. This text provides a comprehensive analysis of antipsychotic medications, covering historical, social, and scientific viewpoints on this important and controversial class of medications.

Antipsychotics are unique drugs with the ability to alter how people think and communicate. As a result, physicians must weigh a range of implications when prescribing antipsychotics. Antipsychotics: History, Science, and Issues offers a robust explanation of antipsychotic medications that covers the historical, ethical, medical, legal, and scientific dimensions of antipsychotics.

The chapters explore topics ranging from the science of how examples of this class of drug actually work in the body to the social and legal implications of antipsychotics, making this subject understandable and relatable for lay readers who are not mental health practitioners. Readers will learn why prescribing antipsychotics is often a difficult decision due to the inherent risks of giving these medications to different types of patients and appreciate how mental health laws impact psychiatrists' prescribing practices.

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Antipsychotics: History, Science, and Issues

Antipsychotics: History, Science, and Issues

Antipsychotics: History, Science, and Issues

Antipsychotics: History, Science, and Issues

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Overview

The problem of serious mental illness is a widely discussed topic in the media and popular culture. This text provides a comprehensive analysis of antipsychotic medications, covering historical, social, and scientific viewpoints on this important and controversial class of medications.

Antipsychotics are unique drugs with the ability to alter how people think and communicate. As a result, physicians must weigh a range of implications when prescribing antipsychotics. Antipsychotics: History, Science, and Issues offers a robust explanation of antipsychotic medications that covers the historical, ethical, medical, legal, and scientific dimensions of antipsychotics.

The chapters explore topics ranging from the science of how examples of this class of drug actually work in the body to the social and legal implications of antipsychotics, making this subject understandable and relatable for lay readers who are not mental health practitioners. Readers will learn why prescribing antipsychotics is often a difficult decision due to the inherent risks of giving these medications to different types of patients and appreciate how mental health laws impact psychiatrists' prescribing practices.


Product Details

ISBN-13: 9781440839894
Publisher: ABC-CLIO, Incorporated
Publication date: 01/26/2017
Series: The Story of a Drug
Sold by: Barnes & Noble
Format: eBook
Pages: 234
File size: 2 MB

About the Author

Jeffrey Kerner, MD, is an attending psychiatrist at Montefiore Medical Center, Bronx, NY. He is forensic coordinator of the Inpatient Unit at MMC-Wakefield and assistant professor of psychiatry and behavioral sciences at Albert Einstein College Of Medicine.

Bridget McCoy, MD, is a general adult psychiatry resident at Montefiore Medical Center, Bronx, NY.

Table of Contents

Series Foreword ix

Acknowledgments xi

Introduction xiii

Chapter 1 Case Studies 1

Case 1 Jimmy 1

Case 2 Bobby 7

Case 3 George 14

Chapter 2 What Are Antipsychotics? 19

Psychotic Disorders and the Symptoms of Psychosis 19

Treatment of Psychosis: From Exorcism to Antipsychotics 25

Typical Antipsychotics: The Beginning 28

Atypical Antipsychotics: As the Story Continues… 42

Chapter 3 Antipsychotics: A Brief History 51

Early Biologic Remedies: The Original Antipsychotics 53

"A Drug in Search of an Illness": Developing Antipsychotic Medications 57

Chlorpromazine Rises 60

Side Effects Emerge 64

Competition for Chlorpromazine 65

How Antipsychotics Are Used Today: Bridging Past and Future 69

Chapter 4 How Antipsychotics Work 73

Parts of the Brain 74

What Are Neurotransmitters and What Do They Do? 76

Neurotransmitters Affected by Antipsychotics 77

Other Potential Targets 91

Chapter 5 Effects and Applications 93

Therapeutic Effects of Antipsychotics 93

How Well Do Antipsychotics Work? 103

Indications for Medical Use 107

Antipsychotic Use in Special Groups 117

Chapter 6 Risks, Misuse, and Overdose 123

Side Effects 123

Misuse of Anripsychotics 147

Antipsychotic Overdose and Toxicity 148

Chapter 7 Production, Distribution, and Regulation 151

Pharmaceutical Industry 151

Antipsychotics in Nursing Homes 159

Prior Authorization 160

The Unique Case of Clozapine 161

AIMS and Metabolic Monitoring 165

Chapter 8 The Social Dimensions of Antipsychotics 169

Deinstitutionalization 170

Antipsychotics and the Doctor-Patient Relationship 174

Legal and Ethical Implications of Antipsychotics 178

Antipsychotics and Political Dissent 184

Antipsychotics and the Elderly 185

Antipsychotics and Children 186

When to Treat? The Implications of the Initiation of Antipsychotic Treatment 188

The Business of Antipsychotics 189

Mental Illness and Violence 190

Chapter 9 The Future of Antipsychotics 193

Where Are Antipsychotics Failing? 194

Pathophysiology of Chronic Psychotic Disorders 198

New Medications on the Horizon 200

Better Routes of Administration 205

Use in Nonpsychotic Disorders 211

Directory of Resources 217

Glossary 221

Bibliography 227

Index 231

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