Atropisomerism And Axial Chirality

by Jose M Lassaletta

Overview

Chapter contribution from Ben Feringa, Nobel Laureate in Chemistry 2016.Atropisomerism and Axial Chirality provides a global survey of the chemistry of axially chiral compounds including biaryls, heterobiaryls, non-biaryl atropisomers, allenes and spyrocyclic derivatives. From the perspective of a synthetic organic chemist, this book provides a unique compilation of the available methodologies for their synthesis, with emphasis on the most efficient and modern strategies, a review of the huge amount of practical applications in the field of asymmetric catalysis, either as transition metal ligands or as organocatalysts, and an overview of their occurrence as bioactive compounds and natural products.The first of its kind, this book serves as a general introduction and a practical reference to advanced chemistry students and researchers, while also offering creative ideas for further developments in the field.

Product Details

ISBN-13:	9781786346452
Publisher:	World Scientific Publishing Europe Ltd
Publication date:	06/06/2019
Pages:	676
Product dimensions:	6.00(w) x 9.00(h) x 1.44(d)

Table of Contents

Preface; Asymmetric Synthesis of Axially Chiral Biaryls and Heterobiaryls; Applications of Axially Chiral Organocatalysts; Axially chiral P, P-Ligands for Asymmetric Metal-Catalyzed Reactions; Axially Chiral Monodentate Phosphorus Ligands for Asymmetric Metal-Catalysed Reactions; Axially Chiral P, X-Ligands (X=N, O and S) for Asymmetric Metal-Catalyzed Reactions; Axially Chiral X, X-Ligands (X=N, O and S) for Asymmetric Metal-catalyzed Reactions; Non-Biaryl Atropisomers: Anilides, Amides, Lactams and Analogues with C-C and C-X Stereogenic Axis; Axial Chirality Beyond Atropoisomerism: Allenes and Related Compounds; Axially Chiral Natural Products and Bioactive Compounds