Biophysics of DNA-Protein Interactions: From Single Molecules to Biological Systems

This book presents a concise overview of current research on the biophysics of DNA-protein interactions. A wide range of new and classical methods is presented by authors investigating physical mechanisms by which proteins interact with DNA. For example, several chapters address the mechanisms by which proteins search for and recognize specific binding sites on DNA, a process critical for cellular function. Single molecule methods such as force spectroscopy as well as fluorescence imaging a...