ISBN-10:
0521154464
ISBN-13:
9780521154468
Pub. Date:
06/24/2010
Publisher:
Cambridge University Press
Brain Drug Targeting: The Future of Brain Drug Development

Brain Drug Targeting: The Future of Brain Drug Development

by William M. Pardridge

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Product Details

ISBN-13: 9780521154468
Publisher: Cambridge University Press
Publication date: 06/24/2010
Edition description: Reissue
Pages: 376
Product dimensions: 6.70(w) x 9.50(h) x 0.90(d)

Table of Contents

Prefaceix
List of abbreviationsxi
1Drug targeting, drug discovery, and brain drug development1
2Invasive brain drug delivery13
3Lipid-mediated transport and carrier-mediated transport of small molecules36
4Receptor-mediated transcytosis of peptides82
5Vector discovery: genetically engineered Trojan horses for drug targeting126
6Linker strategies: the engineering of multifunctional drug formulations155
7Protein neurotherapeutics and peptide radiopharmaceuticals186
8Antisense neurotherapeutics and imaging gene expression in vivo221
9Gene therapy of the brain251
10Blood-brain barrier genomics275
References301
Index347

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