According to the National Institutes of Health, there are sixty to seventy million people affected by digestive diseases in the United States. The old proverb tells us “you are what you eat,” and the latest science shows that this may be truer than we even thought. Diet has a profound effect on both physical and mental health. Most of the body’s immune system is in the gut, so pathology and dysfunction in the gut and imbalanced gut flora can cause neuroinflammation and possibly even neurodegenerative disease over time.
Featuring contributions from dozens of experts on gut disorders and related physical, mental, and behavioral health, this book will fascinate you as you read about the intriguing world of bad bugs, cytokine storms, and the environment in your belly that influences your brain. From the microscopic world of Clostridium to the complex communities of biofilm, Bugs, Bowels, and Behavior emphasizes one simple fact: The gut is connected to the brain.
|Product dimensions:||6.00(w) x 8.90(h) x 0.90(d)|
About the Author
Claire I. Viadro, MPH, PhD, is a professional writer and editor with two advanced degrees in public health. Her writing focuses primarily on women’s and children’s health. Claire currently serves as the editor of Autism Science Digest.
Lauren Underwood, PhD, received her doctorate from Tulane University and is currently working for NASA. Dr. Underwood coauthored several chapters in Understanding Autism for Dummies and has served as the scientific consultant for Autism Science Digest.
Martha Herbert, PhD, MD, is a pediatric neurologist and researcher at Massachusetts General Hospital, Harvard Medical School, and the Harvard-MIT HST Martinos Center for Biomedical Imaging. Her TRANSCEND
Research Program uses advanced brain imaging techniques and biomarkers to look at the relationship of metabolism, perfusion, and brain function.
Table of Contents
Foreword: Bugs, Bowels, Brains, Behavior and the Emergence of Brain-Body-Planet Medicine Martha Herbert ix
Introduction Lauren Underwood xiii
Chapter 1 The Biochemical Connection between the Gut and the Brain: How Food, Bugs, and the Gut Barrier Affect Health, Behavior, and Cognition Geri Brewster 1
Chapter 2 Theories of Gut-Brain Axis Involvement in Childhood Developmental Disorders Arthur Krigsman 27
Chapter 3 Role of the GI Tract in Neuroepigenetic Regulation During Early Development and Its Implications for Autism Richard C. Deth Nathaniel W. Hodgson Stephen Walker Arthur Krigsman Malav S. Trivedi 47
Chapter 4 Biofilm: A Cause of Chronic Gastrointestinal Issues in ASD John H. Hicks 69
Chapter 5 Old Friends, New Treatment: Helminthic Therapy in Autism Judith Chinitz 83
Chapter 6 The Not So Small World of Gut Microbes: How They Influence Behavior and the Brain in Big Ways James Jeffrey Bradstreet 97
Chapter 7 Gut Microbiota-Brain Connection Thomas J. Borody Jordana Campbell 117
Chapter 8 FMT: A Parent's Account of a Fecal Microbiota Transplantation Done for a 15-year-old Female Presenting with Autism, Chronic Constipation, and Very Low Energy Levels Michael F. Wagnitz 131
Chapter 9 The Role of Intestinal and Other Microbes in Autism and Other Diseases Affecting the Central Nervous System Sydney M. Finegold 135
Chapter 10 Gastrointestinal Balance and Neurotransmitter Formation Amy Yasko Nancy Mullan 169
Chapter 11 Interrelationships among the Gut, Mitochondrial Function, and Neurological Sequelae Daniel A. Rossignol 199
Chapter 12 Milk: Effects & Implications for Autism and Other Disorders Krystal D. Dubé Richard C. Deth 217
Chapter 13 Is It Ever Too Late? Using a Biomedical Approach and Dietary Intervention to Treat Children and Adults with Autism Pamela Ferro Raman Prasad Carol Wester 227
Chapter 14 Diagnosing and Treating Inflammatory Bowel Disease in the Genomic Era Stephen Walker 245
Chapter 15 Food Allergy and the Gut-Brain Axis Andrew Wakefield 257