Besides applications in pharmaceutical analysis and bioanalysis, recent implementations in food science, forensic analysis, analysis of intact proteins, metabolomics and proteomics are highlighted. MS is a perfectly appropriate detection system for CE, as efficient separation is coupled to sensitive and selection detection. Moreover, MS can provide structure information on the separated compounds. CE-MS has now been developed into a strong hyphenated system complementary to LC-MS. This monograph is an unique source of knowledge for everyone dealing with and interested in CE-MS.
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About the Author
Prof. de Jong is (co-)author of more than 300 papers in various scientific journals and some book chapters. He is co-author of a book on chromatography and was editor of the Journal of Chromatography B from 1998 to 2003. His research interests encompass separation techniques and their applications in pharmaceutical analysis, bioanalysis and analysis of biomacromolecules.
Table of Contents
Detection in Capillary Electrophoresis - An Introduction
Electrospray Ionization Interface Development for Capillary Electrophoresis-Mass Spectrometry
Sheath Liquids in CE-MS: Role, Parameters, and Optimization
Recent Developments of Microchip Capillary Electrophoresis Coupled with Mass Spectrometry
On-line Electrophoretic, Electrochromatographic, and Chromatographic Sample Concentration in CE-MS
CE-MS in Drug Analysis and Bioanalysis
Intact Protein Analysis by Capillary Electrophoresis - Mass Spectrometry
CE-MS in Food Analysis and Foodomics
CE-MS in Forensic Sciences with Focus on Forensic Toxicology
CE-MS in Metabolomics
CE-MS for Clinical Proteomics and Metabolomics: Strategies and Applications