Case Files Biochemistry 3/E

by Eugene C. Toy, William E. Seifert Jr., Henry W. Strobel, Konrad P. Harms

Overview

LEARN BIOCHEMISTRY IN THE CONTEXT OF REAL-LIFE PATIENTS AND PREPARE FOR THE USMLE Step 1

Experience with clinical cases is key to excelling on the USMLE Step 1 and shelf exams, and ultimately to providing patients with competent clinical care. Case Files: Biochemistry provides 53 true-to-life cases that illustrate essential concepts in this field. Each case includes an easy-tounderstand discussion correlated to essential basic science concepts, definitions of key terms, biochemistry pearls, and USMLE-style review questions. With Case Files, you'll learn instead of memorize.

• Learn from 53 high-yield cases, each with board-style questions and key-point pearls
• Master complex concepts through clear and concise discussions
• Practice with review questions to reinforce learning
• Polish your approach to clinical problem-solving
• Perfect for medical and dental students preparing for course exams and the Boards

Product Details

ISBN-13:	9780071794893
Publisher:	McGraw Hill LLC
Publication date:	09/22/2014
Series:	LANGE Case Files
Sold by:	Barnes & Noble
Format:	eBook
Pages:	480
File size:	10 MB

About the Author

Eugene C. Toy, MD is a dual certified family physician and ob/gyn. He is the John S. Dunn Senior Academic Chair and Program Director of the Obstetrics and Gynecology Residency Program; Vice Chair of Academic Affairs in the Department of Obstetrics and Gynecology at The Methodist Hospital--Houston; Clerkship Director and Assistant Clinical Professor in the Department of Obstetrics and Gynecology at The University of Texas--Houston Medical School (Houston, Texas).
William E. Seifert, Jr., PhD is Senior Lecturer and Medical Biochemistry Course Director in the Department of Biochemistry and Molecular Biology at The University of Texas—Houston Medical School.
Henry W. Strobel, PhD is Professor in the Department of Biochemistry and Molecular Biology; Assistant Dean for Student Affairs; and Associate Dean for Faculty Affairs at The University of Texas—Houston Medical School.
Konrad P. Harms, MD is Associate Program Director and Director of Academic Development for the Obstetrics and Gynecology Residency Program at The Methodist Hospital in Houston, Texas.

Table of Contents

Cases:
1. Sickle Cell Disease
2. Adenosine Deaminase Deficiency
3. Methotrexate and Folate Metabolism
4. Folic Acid Deficiency
5. HIV
6. Herpes Simplex Virus/Polymerase Chain Reaction
7. Hyperthyroidism/Steroid Messenger Regulatin of Translation
8. Cystic Fibrosis
9. Erythromycine and Lyme Disease
10. Maple Syrup Urine Disease
11. Oncogenes and Cancer
12. Thalassemia/Oligonucleotide Probe
13. Fragile X Syndrome
14. Anaerobic Metabolism
15. Thiamine Deficiency
16. Cyanide Poisoning
17. Alcoholic Ketoacidosis
18. Malignant Hyperthemia
19. Pancreatitis
20. Acute Fatty Liver in Pregnancy
21. Rhabdomyolysis
22. Type 2 Diabetes
23. Hemolytic Anemia
24. Fructose Intolerance
25. Irritable Bowel Syndrome
26. Somogyi Effect
27. Myocardial Infarction
28. Tay-Sachs Disease
29. Sanfilippo Syndrome
30. Hypercholesterinemia
31. Gallstones
32. NSAID-Associated Gastritis
33. Glucose-6-Phosphate Dehydrogenase Deficiency
34. Statin Medications
35. Hypertriglyceridemia (Lipoprotein Lipase Deficiency)
36. Starvation
37. Cirrhosis
38. Phenylketonuria
39. Anorexia Nervosa
40. Acetaminophen Overdose
41. Vegetarian Diet (Essential Amino Acids)
42. Cobalamin Deficiency (Vitamin B12)
43. Gout
44. Porphyria (Acute Intermittent Porphyria)
45. Hypothyroidism
46. Diabetes Insipidus
47. Medium Chain Acyl-CoA Dehydrogenase Deficiency
48. Menopause
49. Addison Disease
50. Cushing Syndrome
51. Hyperparathyroidism
52. Pheochromocytoma
53. Pediatric Methemoglobinemia Following Diarrhea

Index

Editorial Reviews

Reviewer: Susan Viselli, Ph.D.(Midwestern University Chicago College of Osteopathic Medicine)
Description: This book provides 53 clinical cases along with discussion of the basic science that relates to the clinical presentation. The previous edition was published in 2008.
Purpose: It is designed to demonstrate the applicability of biochemistry to clinical cases. It aims to teach students how to approach clinical problems and provides multiple-choice questions to test their mastery of the material.
Audience: Aimed at medical students preparing for board exams, this book is most appropriate for health professions students who have a clinical knowledge base and seek a means to review biochemistry. Of the team of four authors, two are physicians and two are faculty in biochemistry departments in medical schools. I see this also a resource for faculty who wish to incorporate clinical cases into their basic sciences courses.
Features: While officially organized into two sections, this book could better be described as having a foreword that consists of three and a half pages of suggestions on how to study, followed by over 400 pages of clinical cases with discussion and practice questions. Summary points called "Biochemistry Pearls" are presented after each case. Section I has three parts, each quite brief, designed to explain the authors' perspective on how best to learn biochemistry and its applications to disease. Section II is composed of the 53 clinical cases, covering a broad and comprehensive range of diseases and presentations, each followed by learning objectives, definitions of key terms, a discussion, and a set of multiple-choice comprehension questions with answer explanations, and then by the pearls.
Assessment: There are many books available that aim to help students prepare for licensing examinations. With the movement toward maximizing clinical applications in medical licensing exams, exposure to a wide variety of clinical cases and to questions that assess a student's ability to apply the information can be very helpful. This title achieves this goal to some extent, by providing a wide variety of cases, definitions of key terms, learning objectives, and discussion. However, it seems to fall short in the types of review questions it presents. Many of the items are of the recall type and very few ask for interpretation of laboratory data or require higher levels of reasoning, unlike many questions on licensing exams. Therefore, I caution students using the review questions in this book to prepare for exams not to expect that they are of the same difficulty or nature as those they will encounter on the actual licensing exam.

Doody's Review Service