Cell Cycle and Cell Differentiation

It is instructive to compare the response of biologists to the two themes that comprise the title of this volume. The concept of the cell cycle-in contra­ distinction to cell division-is a relatively recent one. Nevertheless biologists of all persuasions appreciate and readily agree on the central problems in this area. Issues ranging from mechanisms that initiate and integrate the synthesis of chro­ mosomal proteins and DNA during S-phase of mitosis to the manner in which assembly of micro...