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Changing the Course of Autism: A Scientific Approach for Parents and Physicians
386
by Bryan Jepson, Jane Johnson, Katie Wright (Foreword by)
Bryan Jepson
![Changing the Course of Autism: A Scientific Approach for Parents and Physicians](http://img.images-bn.com/static/redesign/srcs/images/grey-box.png?v11.8.5)
Changing the Course of Autism: A Scientific Approach for Parents and Physicians
386
by Bryan Jepson, Jane Johnson, Katie Wright (Foreword by)
Bryan Jepson
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Overview
In Changing the Course of Autism, Dr. Bryan Jepson and Jane Johnson reveal the biological and neurological conditions behind autism spectrum disorders.
Foreword by Katie Wright, daughter of the founders of Autism Speaks
Rather than simply masking symptoms with drugs like Ritalin and Prozac, Dr. Bryan Jepson and Jane Johnson explain that autism can be treated by reducing the neurological inflammation that is part of the disease process. The authors have seen autistic behaviors improve dramatically or disappear completely with appropriate medical treatment. The book reviews the medical literature regarding the biological nature of the disease, including the potential connection between vaccines and autism.
“This book will be the new PDR of autism for parents and physicians. Incredibly well referenced and easy to understand, it challenges long-held beliefs about this condition and introduces us to the new medical model of autism. An important book that every professional and family member who deals with autism must own.” —Lee Grossman, former president and CEO, Autism Society of America
“The idea that the suffering of autism could be rooted in environmental injuries poses a huge challenge to medicine, science and society. Opening our hearts and minds to fresh thinking is the only way forward. Dr. Jepson’s information-filled book moves the reader through the discomfort of painful news to a framework for constructive responses.” —Martha Herbert, M.D., Ph.D., co-author of The Autism Revolution
“The parent of an autistic child, Jepson encourages physicians and parents to view autism ‘as a medical illness, not just a behavior disorder.’ He discusses the neurological, gastrointestinal, genetic, and environmental issues that complicate our understanding of autism.” —Library Journal
Foreword by Katie Wright, daughter of the founders of Autism Speaks
Rather than simply masking symptoms with drugs like Ritalin and Prozac, Dr. Bryan Jepson and Jane Johnson explain that autism can be treated by reducing the neurological inflammation that is part of the disease process. The authors have seen autistic behaviors improve dramatically or disappear completely with appropriate medical treatment. The book reviews the medical literature regarding the biological nature of the disease, including the potential connection between vaccines and autism.
“This book will be the new PDR of autism for parents and physicians. Incredibly well referenced and easy to understand, it challenges long-held beliefs about this condition and introduces us to the new medical model of autism. An important book that every professional and family member who deals with autism must own.” —Lee Grossman, former president and CEO, Autism Society of America
“The idea that the suffering of autism could be rooted in environmental injuries poses a huge challenge to medicine, science and society. Opening our hearts and minds to fresh thinking is the only way forward. Dr. Jepson’s information-filled book moves the reader through the discomfort of painful news to a framework for constructive responses.” —Martha Herbert, M.D., Ph.D., co-author of The Autism Revolution
“The parent of an autistic child, Jepson encourages physicians and parents to view autism ‘as a medical illness, not just a behavior disorder.’ He discusses the neurological, gastrointestinal, genetic, and environmental issues that complicate our understanding of autism.” —Library Journal
Product Details
ISBN-13: | 9781591811008 |
---|---|
Publisher: | Sentient Publications |
Publication date: | 10/19/2023 |
Sold by: | Barnes & Noble |
Format: | eBook |
Pages: | 386 |
Sales rank: | 797,832 |
File size: | 2 MB |
About the Author
Jane Johnson became interested in medical treatment for learning disabilities in 2000, when her son was diagnosed with non-verbal learning disorder (NLD). In her effort to educate herself, she became more and more alarmed at the epidemic growth of the prevalence of developmental disorders. She is the Co-Managing Director of the Board of Thoughtful House. She lives in New York City with her husband and her three children.
Table of Contents
Foreword xiii
Introduction: Coming to Terms with Autism 1
An Important Note to Readers 8
The Rise and Fall of the "Refrigerator Mother" Theory 11
Kanner's Diagnosis 11
The Refrigerator Mother Theory 17
Progress in Behavioral Intervention 18
Autism Isn't Purely Genetic 20
The Autism Epidemic 24
Concern in California 25
The Mind Institute Study 28
Diagnostic Substitution? 30
What about the Rest of the Country? 31
What about Other Countries? 33
Changes in the Diagnostic Criteria 34
Other Explanations? 35
The Hidden Horde Theory Refuted 37
California Update 38
The Autism Crisis 40
Autism Is a Disease, Not A Disability 42
Autism: An Environmental Illness 42
Disease, Not Disability 44
The Multiple Hit Hypothesis 45
Basics of the Immune System 47
The First Line of Defense 48
The Non-Specific or Innate Immune Response 49
The Antigen-Specific or Adaptive Immune Response 50
Antigen-Presenting Cells (APCs) 50
T-Cells 51
B-Cells 51
Th1 Vs. Th2 Response 53
Other Immune Cells 55
The Problem of Immune Dysregulation 56
Do Individuals with Autism Have Immune Dysregulation? 58
Excessive Inflammation 59
Autoimmune Reactions 60
Food Reactions 61
Abnormal Response to Infections 63
Measles and the MMR Controversy 65
The Epidemiology Wars 67
Biological Plausibility 80
Confirmation 82
Is Autism a Gut Disease? 87
Diagnostic Confirmation of Upper GI Disease 88
Abnormal Stools 89
Autistic Enterocolitis 90
Leaky Gut Syndrome 95
Intestinal Dysbiosis 97
Why Can't They Detoxify? 100
Detoxification 101 100
The Methylation Cycle 101
The Importance of Glutathione 107
Impaired Methylation in Autism 108
Does Mercury Cause Autism? 112
The Mercury Cycle 113
The Toxicity of Mercury 113
The EPA Reports Concern about Mercury 116
Mercury and Autism 117
What is Thimerosal? 123
Thimerosal Studies 125
Further Evidence Against Mercury 140
Where Does Ethylmercury Go? 140
Is Ethylmercury as Bad as Methylmercury? 144
Cell Death in the Brain and the Immune System 146
Thimerosal Inhibits Glutamate Transport 147
Thimerosal Affects Nerve Differentiation 147
Can You Be Genetically at Risk for Thimerosal Injury? 147
Other Effects of Thimerosal on the Immune System 148
Thimerosal Inhibits Methylation 149
Thimerosal Depletes Intracellular Glutathione in Brain Cells 149
Other Effects of Thimerosal 153
Autistic Children and Mercury Exposure 153
Environmental Mercury Exposure and Autism 157
The Institute of Medicine (IOM) Report 159
Autism and the Brain 164
Neuroanatomy (Brain Structure) 164
Abnormal Neurochemistry 166
Seizures 173
Sleep Disturbances 174
The Autism Web-Making Sense of the Disease 176
Treating Autism 181
The Multi-Tiered Treatment Approach 183
Correcting Nutritional Deficiencies 188
Vitamins 190
Minerals 199
Omega Fatty Acids 203
Essential Amino Acids 205
Other Nutrients 207
Providing a Good Diet 209
Treating the Gut 210
Treating Dysbiosis 210
Digestive Enzymes 214
Fixing a Leaky Gut 215
Treating Constipation 215
Treating Reflux 216
Treating Autistic Enterocolitis 216
Detoxification 220
Preventing Oxidative Stress 220
Supporting the Detoxification Pathway 222
Removing Toxins 227
Treating the Immune System 234
Immune System Support 234
Removing Immune Triggers 237
Breaking the Inflammatory Cycle 241
Treating the Brain 246
Removing False Neurotransmitters and Neurotoxins 247
Modulating Neurotransmitters 249
Neurohormones 254
Supply the Brain with Oxygen 256
Treating Seizures 257
Lessons from Israel 259
Parent Ratings of Behavioral Effects of Biomedical Interventions 262
DSM III-R and DSM IV Criteria for Autism 264
Notes 267
Glossary 323
Acknowledgments 341
Permissions 343
Index 349
About Thoughtful House 355
About the Authors 357
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