Combined Spinal-Epidural Anesthesia

The first epidural analgesia was done by Corning in 1885 inadvertently. Lumbar dural puncture was introduced in 1891 by Wynter in England and Quincke in Germany. Von Ziemssen in 1894 suggested the feasibility of injecting drugs by means of lumbar dural puncture. Bier, a surgeon at the Royal Chirurgical Clinic in Kiel, was the first to inject cocaine into the spinal space. It was between August 16 and 27, 1898. It took 38 years since Corning's discovery of the epidural analgesia and 25 years...