Computational Design of Ligand Binding Proteins

This volume provides a collection of prools and approaches for the creation of novel ligand binding proteins, compiled and described by many of today's leaders in the field of protein engineering. Chapters focus on modeling protein ligand binding sites, accurate modeling of protein—ligand conformational sampling, scoring of individual docked solutions, structure—based design program such as ROSETTA, protein engineering, and additional methodological approaches. Examples of applications incl...