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Enkephalins and Endorphins: Stress and the Immune System

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Is this a time for a sleeping giant to rise? We have known since study of the lymphocyte and plasma cells really began in earnest in the early 1940's that the pituitary adrenal axis under intimate control of the hypothalamus could influence immunological functions profoundly. We have also known for at least 20 years in my recollection that female sex hor­ mones can maximize certain immunity functions while male sex hormones tend to suppress many immunological reactions. The thyroid hormones...