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Evolution and Variation of Multigene Families

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During the last decade and a half, studies of evolution and variation have been revolutionized by the introduction of the methods and concepts of molecular genetics. We can now construct reliable phylogenetic trees, even when fossil records are missing, by comparative studies of protein or mRNA sequences. If, in addition, paleon­ tological information is available, we can estimate the rate at which genes are substituted in the species in the course of evolution. Through the application of e...