Fatal Attractions: Protein Aggregates in Neurodegenerative Disorders

by V.M.-Y. Lee (Editor), J.Q. Trojanowski (Editor), L. Buee (Editor), Y. Christen (Editor)

Overview

In this volume are contributions based on a meeting arranged by the WHO and the Fondation IPSEN. The scientists focus on neurodegenerative disorders like Alzheimer's Disease, Chromosome 17-Linked Dementia, Parkinson's Disease and disorders with tauopathies.

Product Details

ISBN-13:	9783642086496
Publisher:	Springer Berlin Heidelberg
Publication date:	12/03/2010
Series:	Research and Perspectives in Alzheimer's Disease
Edition description:	Softcover reprint of hardcover 1st ed. 2000
Pages:	140
Product dimensions:	6.10(w) x 9.25(h) x 0.01(d)

Table of Contents

The Role of—-Synuclein in Parkinson’s Disease: A Biophysical Analogy to A? and Alzheimer’s Disease.- Purification of Lewy Bodies and Identification of—Synuclein as a Major Component of Lewy Bodies.- Mutational Analysis of Tau in Chromosome 17-Linked Dementia.- Missense and Splice Site Mutations in Tau Associated with FTDP-17: Multiple Pathogenic Mechanisms.- Tau Mutations: Genetics and Pathogenetic Mechanisms.- Tauopathies and—-Synucleinopathies.- Distinct Tau Gene Mutations Induce Specific Dysfunctions/Toxic Properties in Tau Proteins Associated with Specific FTDP-17 Phenotypes.- Neurodegenerative Disorders with Tauopathies: Mad Tau Diseases?.- Tau Protein: Role in Intracellular Traffic and Development of Cell Polarity.