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This book is about one plasma protein, fetuin. Once the connection was made between fetuin and its human counterpart - alpha2HS glycoprotein - , structural analysis showed fetuin to be a member of the cystatin family. First descriptions of fetuin implicated its role in development. Fetuin is a major component of fetal calf serum and was thought to have special growth-promoting activity. The main interest in fetuin stems from the observation that in the early developing brain fetuin is expre...