Fundamentals of Nuclear Pharmacy

by Gopal B. Saha

Overview

Currently an estimated 17 million nuclear medicine procedures are performed each year in the US and constantly evolving, as new radiopharmaceuticals and imaging techniques are introduced for better diagnosis and treatment of human diseases. In keeping up with new developments, the Seventh Edition of Fundamentals of Nuclear Pharmacy chronicles the advancements in radiopharmaceuticals and their use in clinical applications. It discusses basic concepts such as the atom, radioactive decay, instrumentation and production of radionuclides, and explores the design, labeling, characteristics and quality control of radiopharmaceuticals. Radiation regulations and diagnostic and therapeutic applications of radiopharmaceuticals are detailed.

Thoroughly updated, the Seventh Edition includes new topics such as alternative productions of ⁹⁹Mo; production of ⁶⁴Cu, ⁸⁶Y, ⁸⁹Zr, ¹⁷⁷Lu, ²²³Ra; synthesis and clinical uses of new radiopharmaceuticals such as DaTscan, Xofigo, Amyvid, Neuraceq, Vizamyl, Axumin and ⁶⁸Ga-DOTATATE; dosimetry of new radiopharmaceuticals; theranostic agents and translational medicine. It features numerous examples, diagrams, and images to further clarify the information and offers end- of-chapter questions to help readers assess their comprehension of the material. Recognized as a classic text on nuclear chemistry and pharmacy and acclaimed for its concise and easy-to-understand presentation, Fundamentals of Nuclear Pharmacy is an authoritative resource for nuclear medicine physicians, residents, students, and technologists.

Product Details

ISBN-13:	9783319575797
Publisher:	Springer International Publishing
Publication date:	11/15/2017
Edition description:	Seventh Edition 2018
Pages:	428
Product dimensions:	6.10(w) x 9.25(h) x (d)

About the Author

Gopal B. Saha, PhD

Emeritus Staff

Cleveland Clinic

Cleveland, OH, USA

Gopal Saha, PhD, joined the Department of Nuclear Medicine at the Cleveland Clinic as Director of Nuclear Chemistry and Pharmacy in 1984. He established a nuclear pharmacy laboratory with full amenities for routine clinical studies and sponsored clinical trials, which has been highly acclaimed by Nuclear Regulatory Commission and Joint Commission Accreditation of Healthcare Organizations. He is the recipient of the Lifetime Achievement (Basic Science) Award of the Indo-American Society of Nuclear Medicine and of the Lifetime Achievement (Basic Science) Award of the Indo-American Society of Nuclear Medicine.

Table of Contents

The Atom.- Radioactive Decay.- Instruments for Radiation Detection and Measurement.- Production of Radionuclides.- Radionuclide Generators.- Radiopharmaceuticals and Methods of Radiolabeling.- Characteristics of Specific Radiopharmaceuticals.- Quality Control of Radiopharmaceuticals.- Nuclear Pharmacy.- Internal Radiation Dosimetry.- Radiation Regulations, Protection, and Uses.- In Vitro and In Vivo Nonimaging Tests.- Diagnostic Uses of Radiopharmaceuticals in Nuclear Medicine.- Molecular Imaging.- Therapeutic Uses of Radiopharmaceuticals in Nuclear Medicine.- Adverse Reactions to and Altered Biodistribution of Radiopharmaceuticals.

Editorial Reviews

New edition of a text (previous ed., 1985) written in an integrated form progressing from the basic concept of atomic structure to the practical clinical uses of radiopharmaceuticals. Annotation c. Book News, Inc., Portland, OR (booknews.com)

Booknews

Reviewer: William C Cole, Ph.D.(University of Colorado Health Sciences Center)
Description: This is the fifth edition of a standard textbook of nuclear pharmacy that has been a mainstay of graduate training since 1979. The dynamic nature of radiopharmaceutical development makes this new edition both welcome and needed.
Purpose: This book provides the basic scientific, clinical, and regulatory framework for an introduction to the practice of nuclear pharmacy. As such, the revisions in this edition incorporate newer radiopharmaceuticals and regulatory information necessary for a current understanding of the field. Elimination of older/obsolete radiopharmaceuticals from those presented in previous editions help to clean up the otherwise large compendium of agents historically used in nuclear medicine and pharmacy.
Audience: The book is intended for a broad population of readers to include nuclear medicine residents and technologists as well as a reference for radiologists. It would also be appropriate for a survey course in the initial training of nuclear pharmacists. Due to the breadth of the material covered and the intended audience, one cannot expect to find an in-depth treatment of many of the covered topics. By design, it avoids mathematical rigor in the discussion of nuclear physics and chemistry.
Features: As an introduction, this book provides rather comprehensive coverage of all relevant material needed for nuclear pharmacy. In addition to a basic discussion of the nature of radioactivity and atomic physics, this book addresses fundamental information about radiation detection and measurement, regulations regarding the medical use of radioactive materials, short descriptions of the nature and clinical utility of a large list of radiopharmaceuticals, and a glimpse into the future of molecular imaging. This reviewer would have enjoyed a brief discussion of the history of radioactive materials in medicine. Some of the clinical images presented could have better reflected the current state-of-the art with respect to image quality. As appropriate for a textbook, each chapter concludes with a set of questions. Thankfully, an appendix of the answers is also provided.
Assessment: This is a welcome update of the four previous editions. Students of nuclear pharmacy can rely on the accuracy of the content and breadth of the topics covered. This work has become a true accepted standard in the field and this new edition lives up to the laudable goals of past editions.

Doody's Review Service