Histone and Non-Histone Reversible Acetylation in Development, Aging and Disease

This volume explores various aspects of reversible acetylation of histone and non-histone proteins, focusing on their roles in development, ageing and disease progression.

It examines the biological consequences of modulating acetylation levels by histone acetyltransferases (HATs) and histone deacetylases (HDACs). Covered are manipulations at multiple levels, from in vitro and in vivo studies to clinical trials and FDA-approved therapies.

The book is divided in four parts:

• Part I provides...