Histone Methyltransferases: Methods and Protocols

This volume provides methods used to investigate histone methyltransferase function. Chapters guide readers through a comprehensive set of approaches that detail phylogenetic diversity, histone demethylase activities in vitro, generating chromatin substrates, auto—methylation, quantification of metabolites, protein purification, crystallization, X—ray structure, cryogenic electron microscopy, assessing genome—wide patterns, CUT&Tag in mouse embryonic tissues, chemical biology approaches, pe...