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I Domains in Integrins

By Donald Gullberg (Editor)
Hardcover
$169.00
By Donald Gullberg (Editor)
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In vertebrates, the integrin family includes 24 members. As the alpha-chains were sequenced, some were observed to have an inserted domain similar to the A domain in several matrix and complement proteins. This inserted ligand binding domain is interactive and was called the I domain in integrins. More recently structural data have shown that an integrin beta-chain also contains an I domain. Nine of the currently known 18 alpha-chains contain an I domain.

This book systematically goes thro...

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