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Immediate Early Genes in Sensory Processing, Cognitive Performance and Neurological Disorders

By Raphael Pinaud (Editor), Liisa A. Tremere (Editor)
Paperback
$169.99
By Raphael Pinaud (Editor), Liisa A. Tremere (Editor)
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Immediate early genes (IEGs) are a class of genes that are rapidly expressed without new protein synthesis and, in most cases, in direct response to synaptic input. The most widely studied IEGs in neurobiology encode transcription factors, with two popular examples being c-fos and NGFI-A (a.k.a., zif268 , egr-1, krox-24 and zenk). The activity-dependent expression of most inducible transcription factors has enabled neuroscientists to use their expression as mapping tools for neuronal activa...

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