A look at the future of medicine based on cutting-edge stem cell research
• Shares Dr. Biava’s groundbreaking research on stem cell differentiation stage factors (SCDSFs) as a cellular “reprogramming” treatment for cancer and other degenerative diseases
• Explains how SCDSFs restore communication between cells and the epigenetic code, the information that programs the normal function and growth of every living cell
• Explores how the universe operates like a cosmic information-network and how this new scientific worldview will shape the future of healing and medicine
The universe is not a mechanical system of matterit operates like a cosmic network that runs on and is connected by information. Information “in-forms” and underlies all of the physical world, including the human body. In this book, Pier Mario Biava, M.D., and Ervin Laszlo, Ph.D., show how this “information” worldview can be applied to healing and medicine and, specifically, how it underlies a revolutionary new approach to cancer and disease treatment, one that works directly with the epigenetic codethe information that programs the function and growth of every living cell.
The authors explain how tumor growth and cellular dysfunction are manifestations of disconnections in the information network of an organism. Unveiling Dr. Biava’s groundbreaking research on stem cell differentiation stage factors (SCDSFs), they explain how SCDSFs work directly as epigenetic regulators to reconnect aberrant cells to the body’s information network and reset them to their original functionin the case of cancer cells transforming them from malignant to benign, from dysfunction back to normalcy and health. Dr. Biava’s research on SCDSFsderived from Zebrafish embryos, which have a very high percentage of proteins identical with those of human beingshas shown good success in reprogramming and inhibiting cancer cells in clinical trials with patients with advanced liver cancer, as well as success in in vitro studies with 7 different human tumor lines. SCDSFs have also shown promise in the treatment of chronic diseases such as psoriasis and neurodegenerative diseases. This research will also allow the development of new treatments for Alzheimer’s, Parkinson’s, and multiple sclerosis.
Unveiling the holistic future of medicine, the authors show how we will no longer need to approach the treatment of cancer and other degenerative diseases as a “fight,” but as a restoration of our cells’ original programming. With the advent of Information Medicine, we now have the power to program ourselves to heal.
|Publisher:||Inner Traditions/Bear & Company|
|Product dimensions:||5.90(w) x 8.70(h) x 0.80(d)|
About the Author
Ervin Laszlo, Ph.D., is a philosopher and systems scientist. He has published more than 75 books and over 400 articles and research papers. He lives in Tuscany. Pier Mario Biava, M.D., has been studying the relationship between cancer and cell differentiation for more than 3 decades. The author of over 100 scientific publications and 6 books, he works at the Institute of Research and Treatment in Milan.
Read an Excerpt
Information Medicine in Clinical Practice
The application of new paradigm medicine to clinical practice is based on the realization that the ordering-structuring factor in the universe Bohm called “in-formation,” and traditional wisdom named chi or qi (or prana or etheric factor), is the key to maintaining the integrity and safeguarding the health of organisms. Clinical experience confirms the healing power of nature’s in-formation, and the importance of using it in addition to, or in concert with, established methods.
The information contextualized by cells and cellular systems is not limited to the classically recognized bio-physiological aspects of the body. The content of the information that directs choices in the organism is supra-biological: in the last count, it is the effect of the cosmic attractor that forms and structures processes in the universe.
It is now recognized that the causes of disease may be more than bacterial and viral: there may be deficiencies and imbalances in the organism that are not evident on the biochemical level. Subliminal psycho-emotional causes could also manifest as disease. And there may be personal lifestyle and environmental factors that impact negatively on the organism. These indicate inadequate in-formation by the attractor that structures systems in space and time.
In-formation guides formative processes throughout the organism as well as between organisms. It acts on the epigenetic system, the system that guides the activation and suppression of particular geneswhich in turn regulates the functioning of the whole organism. In acting on the epigenetic systemthe system that determines the activation/suppression of particular genes“in-formation” determines the response of the organism to the signals that reach it. In the embryo it determines the process whereby stem cells differentiate into normal cells (kidney, lung, liver, brain, and still other cells). Cellular differentiation involves a complex series of precisely sequenced steps, at the end of which every cell in the developing organism shares the same genetic code. Following cell differentiation in the embryo, the two codes remain aligned and use the same system to receive and decode messages. This enables the diverse types of cells in the embryo to "understand" each other.
Molecules and other factors of the microenvironment carry information, and cells process that information, decoding and integrating it both in regard to its form and its content. The messages elicit responses, and the responses communicate information to all the cells of the body, whether they are proximal or distant.
Communication among cells takes place when the cells are integrated in a body. Through the exchange of messages, cells constitute an integral cognitive network. This network processes information in all species of organism, including the simplest unicellular species.
As already noted, the living organism is more than the sum of its parts. The integrality of the organism ensures that the various chemical and physical-chemical reactions are not expressions of separate events, but result from the fine-tuning of the organism to its intrinsic and extrinsic (internal and external) environment. It allows molecules and cells to adopt behaviors corresponding to their location within the system.
The differentiation of DNA is indispensable for the re-programming of dysfunctional or downright malignant tumor cells toward benign behavior.
Reprogramming Cancer Stem-like Cells
The whole organism, with all its subsystems and organs, is an integral cognitive network, and in the case of a diseases such as cancer, information in that system is blocked: it does not govern the behavior of a group of malignant cells. The dialogue between the organism and that group of cells is arbitrarily uncontextualizedinterrupted. The signification-codes have changed; they are not the same as those in healthy, normal cells.
Cancer tumor cells organize their own behavior at the expense of the whole organism. Normally differentiated cells cooperate and their behavior is in harmony with cells in the rest of the organism, whereas cancer cells, not being adequately in-formed, may develop malignancy and adopt counterfunctional behaviors. However, this flaw can be corrected. If the organism is given access to the in-formation that maintains or contributes to the health of the organism, it can re-program its malfunctioning cells.
It is known that during the phase of organogenesis (when the organs are forming) in the embryo, regulatory substances are present that correct alterations caused by carcinogens in the embryo’s stem cells. These substances act on the epigenetic code that regulates gene expression in the embryo. They are stem-cell differentiation stage factors (SCDSFs), and they slow or stop the growth of a variety of tumors.
The behavior of tumor cells cannot be reduced to a problem of cells and genes. An explanation based solely on molecular mechanisms resulting from genetic activity and related growth factors does not clarify the nature of cancer. Cancer is a complex system where contact and communication with the flow of information among organs and systems of organs is interrupted, and the in-formation that structures and governs the living organism is inadequately accessed. As a result the health, and even the survival, of the organism is at risk.
The key discovery of information medicine is that substances produced in the dialogue between mother and embryo are effective instruments for inducing the differentiation of mutant and degenerative stem cells in the embryo. These substances are precisely tuned to the embryo’s developmental stage. When extracted and applied to stem cells in other organisms, including the human, they regulate the developmental program of stem cells in those organisms. Clinical evidence shows that cells obtained at precisely selected phases of organogenesis differentiate and reprogram cancer cells in the host organism, inducing malignant cells to mutate into normal healthy cells.
The new discovery has been tested both in vitro (in the laboratory) and in vivo (under natural conditions). The testing has confirmed the discovery’s effectiveness in cases of serious tumoral and degenerative diseases.
Table of Contents
Foreword by Deepak Chopra, M.D.
The New Paradigm in Science and Medicine
The New Paradigm in Physics
The New Paradigm of Evolution
Information Medicine: The New Paradigm in Health and Healing
Information Medicine in Clinical Practice
Reprogramming Cancer Stem-like Cells
Review of the Experimental Evidence
Conclusions Based on the Experiments
Addendum: Declaration of a Committee of Oncologists
Summing Up: The Meaning of Information Medicine for Our Life and Times
The Scientific Papers of Biava, et al.
Complex Therapeutical Approaches to Complex Diseases
Reprogramming of Normal and Cancer Stem Cells
The Principal Reports
Cancer and Cell-Differentiation: A Model to Explain Malignancy
Stem Cell Differentiation Stage Factors from Zebrafish Embryo: A Novel Strategy to Modulate the Fate of Normal and Pathological Human (Stem) Cells
Getting an Insight into the Complexity of Major Chronic Inflammatory and Degenerative Diseases: A Possible New Systemic Approach to Their Treatment
Cancer: A Problem of Developmental Biology; Scientific Evidence for Reprogramming and Differentiation Therapy
Abstracts of Selected Studies
Stem Cell Differentiation Stage Factors and Their Role in Triggering Symmetry Breaking Processes during Cancer Development
The Role of Neuroendocrine Cells in Prostate Cancer
A Systemic Approach to Cancer Treatment: Tumor Cell Reprogramming Focused on Endocrine-Related Cancers
The Zebrafish Embryo Derivative Affects Cell Viability of Epidermal Cells: A Possible Role in the Treatment of Psoriasis
Cancer Cell Reprogramming: Stem Cell Differentiation Stage Factors and an Agent-Based Model to Optimize Cancer Treatment
Zebrafish Stem Cell Differentiation Stage Factors Suppress Bcl-Xl, Release and Enhance 5-Fu-Mediated Apoptosis in Colon Cancer Cells
Embryonic Morphogenetic Fields Induce Phenotypic Reversion in Cancer Cells
Cancer, Cell Death, and Differentiation: The Role of Epigenetic Code in Tumor Growth Control
Zebrafish Embryo Proteins Induce Apoptosis in Human Colon Cancer Cells (Caco2)
Treatment with Stem Cell Differentiation Stage Factors of Intermediate-Advanced Hepatocellular Carcinoma
About the Authors
Laszlo’s Books on the New Paradigm
Biava’s Books on the New Discovery