Insecticides: Action and Metabolism

Insecticides: Action and Metabolism

by R. D. O'Brien

NOOK Book(eBook)

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Product Details

ISBN-13: 9781483270685
Publisher: Elsevier Science
Publication date: 06/28/2014
Sold by: Barnes & Noble
Format: NOOK Book
Pages: 344
File size: 6 MB

Table of Contents

Preface


Chapter 1 Introduction


Toxicology


Modes of Killing


The Causal Chain Leading to Death


Background Chemistry


Electronic Interpretations


Background Neurobiology


References


Chapter 2 Physical Toxicants


Indifferent Narcotics


The Cutoff Point


The ρ-σ-π Analysis


References


Chapter 3 Organophosphates: Chemistry and Inhibitory Activity


Nomenclature


Nonenzymic Reactions


Reaction with Cholinesterase


References


Chapter 4 Organophosphates: Action, Therapy, and Metabolism


Mode of Action


Therapy


Metabolism


References


Chapter 5 Carbamates


Toxicity


Mode of Action


Mechanism of Cholinesterase Inhibition


Metabolism


Synergism


References


Chapter 6 DDT and Related Compounds


Structure and Chemistry


DDT Analogs


Toxicity


Mechanism of Action


Metabolism of DDT


References


Chapter 7 Cyclodienes


Toxicity


Mode of Action


Metabolism


References


Chapter 8 Nicotinoids


Toxicity


Mechanism of Action


Metabolism


References


Chapter 9 Rotenoids


Mode of Action


Metabolism


References


Chapter 10 Pyrethroids


Mode of Action


Metabolism


References


Chapter 11 Fluorine Compounds


Fluoro-organics


Sodium Fluoride


References


Chapter 12 Lindane and Other Hexachlorocyclohexanes


Toxicity


Mode of Action


Metabolism


References


Chapter 13 Various Compounds


Arsenicals


Silica Aerogels


Ryanodine


DNOC and Dinex


References


Chapter 14 Synergism, Antagonism, and Other Interactions


Inductive Effects


Noninductive Effects


References


Chapter 15 Resistance


DDT Resistance


Cyclodiene Resistance


Lindane Resistance


Organophosphate Resistance


Carbamate Resistance


Conclusion


References


Chapter 16 Selectivity; Penetration


General Principles


Contact of Toxicant and Organism


Penetration into the Organism


Metabolism


Penetration to the Target


Disposal (Storage and Excretion)


Attack upon the Target


Consequences of a Successful Attack upon the Target


References


Chapter 17 Insecticides and Environmental Health


Problems of Human Health


Effects upon Wildlife


References


Author Index


Subject Index






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