Iron Chelation Therapy

Within the last few years, iron research has yielded exciting new insights into the understanding of normal iron homeostasis. However, normal iron physiology offers little protec­ tion from the toxic effects of pathological iron accumulation, because nature did not equip us with effective mechanisms of iron excretion. Excess iron may be effectively removed by phlebotomy in hereditary hemochromatosis, but this method cannot be applied to chronic anemias associated with iron overload. In thes...