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Maturation Phenomenon in Cerebral Ischemia V: Fifth International Workshop April 28-May 1, 2002 Banff, Alberta, Canada

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The Maturation Phenomenon, first described by Ito et al. in 1975, refers to post­ ischemic changes that develop hours or days after an ischemic insult. The delayed neuronal death of CAl pyramidal cells of the hippocampus is a classic example. The report of the phenomenon boosted research in the field, as it became evi­ dent that ischemic damage is not a sudden event but a process potentially suscep­ tible to therapeutic intervention. In September 1990, Ito and collaborators organized the Fi...