Meta-Research: Methods and Protocols

This volume presents state—of—the art design, analysis and integration approaches for biomedical data including novel statistical models for a comprehensive and powerful synthesis and assessment of scientific evidence. Chapters detail principles of systematic reviews, semi—automated tools for systematic searches, fixed— and random—effects meta—analytical models, living systematic reviews, meta—analysis of genetic studies, meta—analysis of pragmatic and explanatory trials, network meta—analy...