Mouse Development: Patterning, Morphogenesis, and Organogenesis

by Janet Rossant, Patrick T. Tam

Overview

This book represents a classic compilation of current knowledge about mouse development and its correlates to research in cell biology, molecular biology, genetics, and neuroscience. Emphasis is placed on the research strategy, experimental design, and critical analysis of the data, disguishing this from other books that only focus on protocols for mouse developmental research. Selected chapters are indexed to electronic databases such as GeneBank, GenBank, Electronic Mouse Atlas, and Transgenic/Knockout, further increasing the utility of this book as a reference.*Broad-based overview of mouse development from fundamental to specialist levels*Extensive coverage of a wide range of developmental mutations of the mouse*Excellent benchmark illustrations of brain, craniofacial, gut and heart development*In-depth experiment-based assessment of concepts in mammalian development*Focus on models of specific relevance to human development*Comprehensive reference to key literature and electronic databases related to mouse development*High-quality full-color production

Product Details

ISBN-13:	9780080537030
Publisher:	Elsevier Science & Technology Books
Publication date:	03/21/2002
Sold by:	Barnes & Noble
Format:	eBook
Pages:	712
File size:	23 MB
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About the Author

gregory.ginsberg.uphs.upenn.edu; Patrick T. Tam [[e-mail]]

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Offers a uniquely research-oriented compilation of knowledge

Table of Contents

Establishment of Body PatternFertilization and Activation of the Embryonic GenomeAsymmetry and Pre-Pattern in Mammalian DevelopmentAnterior Posterior Patterning of the Mouse Body Axis at GastrulationLeft-Right AsymmetryPatterning, Regionalization and Cell Differentiation in the ForebrainEstablishment of Anterior-Posterior and Dorsal-Ventral Pattern in the Early Central Nervous SystemSomitogenesis: Segmentation of the Paraxial Mesoderm and the Delineation of Tissue CompartmentsII.Lineage Specification and DifferentiationExtraembryonic tissuesGerm CellsDevelopment of the Vertebrate Hematopoetic SystemVasculogenesis and AngiogenesisStem Cells of the Nervous SystemCellular and Molecular Mechanisms Regulating Skeletal Muscle DevelopmentChondrogenesis and SkeletogenesisIII.OrganogenesisDevelopment of the Endoderm and its Tissue DerivativesHeart Development: Induction, Myogenesis and PatterningSex Determination and DifferentiationThe Development of the Excretory SystemCraniofacial DevelopmentPituitary Gland DevelopmentSensory Organs: EyeDevelopment of the Mouse Inner EarIntegumentary Structures

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From the Publisher

Offers a uniquely research-oriented compilation of knowledge

Editorial Reviews

Offers an overview of contemporary research in the molecular and cellular aspects of mouse embryonic development. It addresses embryological experimentation, particularly in early embryonic patterning, inductive interactions, and organogenesis. Written by experts in mammalian development, the 23 chapters cover topics including asymmetry and prepattern in mammalian development; left-right asymmetry; segmentation of the paraxial mesoderm and the delineation of tissue compartments; germ cells; vasculogenesis and angiogenesis; development of the endoderm and its tissue derivatives; sex determination and differentiation; craniofacial development; development of the mouse inner ear; and integumentary structures. Color and b&w illustrations throughout. Annotation c. Book News, Inc., Portland, OR (booknews.com)

"...two of the most respected mouse developmental biologists have produced an exceptional book. Right from the outset, it highlights the incredible explosion in our knowledge and understanding of mammalian development over the past decade...will sit very comfortably upon any bookshelf." —Paul Trainor, Stowers Institute for Medical Research for NATURE CELL BIOLOGY (September 2002)"...an excellent resource for scientists interested in any of the selected topics covered by one of the authors." —DOODY'S NOTES (2002)

From the Publisher