Neurodegeneration: Molecular and Cellular Mechanisms

The process of neurodegeneration is a progressive degeneration of neuron cells. It can be categorized into varied levels of neuronal circuitry ranging from molecular to systemic levels. Aging is the primary contributor to neurodegeneration. Neurodegenerative diseases are caused due to genetic mutations. Protein misfolding is another characteristic that is common in such conditions. Intracellular mechanisms such as protein degradation pathways, mitochondrial dysfunction, membrane damage, axo...