Nitric Oxide: Basic Research and Clinical Applications

This book deals with mediation by nitric oxide (NO) of many biological functions. Nitric oxide, initially known as Endothelial Derived Relaxing Factor (EDRF, Furchgott, Zawadzki 1980), six years later was identified as nitric oxide. Nowadays, its significance reached clinical applications. Clinical significance of nitric oxide encompasses: a/ application of NO-donors such as nitroglycerin and other organic nitrates or sydnonimines in cardiovascular diseases b/ exploitation of stimulation of...