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Oncogenes Meet Metabolism: From Deregulated Genes to a Broader Understanding of Tumour Physiology

By Guido Kroemer (Editor), Dominik Mumberg (Editor), Kector Keun (Editor), Björn Riefke (Editor), Thomas Steger-Hartmann (Editor), Kirstin Petersen (Editor)
Hardcover
$169.99
By Guido Kroemer (Editor), Dominik Mumberg (Editor), Kector Keun (Editor), Björn Riefke (Editor), Thomas Steger-Hartmann (Editor), Kirstin Petersen (Editor)
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In 1920s, Otto Warburg described the phenomenon of ‘aerobic glycolysis’, the ability of tumour cells to convert glucose to lactate in the presence of normal oxygen conditions. Warburg’s hypothesis of an altered metabolism in cancer cells found no immediate acceptance, though it was latter confirmed for most human tumours. With the advent of molecular biology the focus in tumour research has shifted towards the search for oncogenes. However, the interest in cancer molecular profiling eventua...

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