P-450 and Chemical Carcinogenesis

P-450 and Chemical Carcinogenesis

by Yusaku Tagashira (Editor)

Paperback(Softcover reprint of the original 1st ed. 1985)

$109.00
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Product Details

ISBN-13: 9781468450323
Publisher: Springer US
Publication date: 03/30/2012
Edition description: Softcover reprint of the original 1st ed. 1985
Pages: 176
Product dimensions: 7.01(w) x 10.00(h) x 0.02(d)

Table of Contents

I. Molecular Multiplicity of Cytochrome P-450.- Physicochemical Properties of Multiple Forms of Cytochrome P-450: A Proposal for the Ligand Structure.- Characteristics of Purified Cytochrome P-450s in Microsomes of Rat Lung and Morris Hepatoma 5123D.- Localization of Cytochrome P-450 in Rat Liver Nuclei: Its Possible Significance in the Chemical Carcinogenesis.- Microsomal Cytochrome P-450 in Higher Plants.- II. Activation of Carcinogenic Compounds by Cytochrome P-450.- Metabolic Activation of Chemical Carcinogens by Two Molecular Species of Cytochrome P-450.- Activation of Carcinogenic Compounds by Purified Cytochrome P-450 in Reconstituted Systems.- Mechanism of Metabolic Activation of Carcinogenic Aromatic Amines.- Mechanism of Metabolic Activation of Aflatoxin B1.- Metabolic Activation of 7,12-Dimethylbenz[a]anthracene and 7-Methylbenz[a] anthracene via Hydroxymethyl Sulfate Esters by P-450-sulfotransferase.- III. Induction and Genetics of Cytochrome P-450.- Induction of Microsomal Cytochrome P-450 in Rat Liver by Chemical Com­pounds.- Molecular Multiplicity and Gene Structure of Microsomal Cytochrome P-450 in Rat Liver.- Author Index.

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