Parkinson's Disease

Parkinson's disease (PD) is a degenerative disorder of the central nervous system, which affects the motor system. In PD, a progressive cell death in the basal ganglia of the brain affects the dopamine secreting neurons present in the substantia nigra pars compacta. This impacts the functioning of the motor, oculo-motor, limbic, associative and orbitofrontal circuits of the brain. As the disease progresses, non-motor functions are also compromised. Symptoms typically appear slowly with time...