Polycystic Ovarian Disease

Polycystic ovarian disease, or polyfollicular ovarian disease, as Dr. Fut­ terweit prefers to call it, is a disease of uncertain etiology and for which numerous modes of therapy have been advanced. Understanding of its pathophysiology should shed light on factors regulating normal ovarian function; the converse is also true. Recent years have brought about great understanding of the neuro­ endocrine regulation of gonadal function, as well as of factors in the microenvironment of the ovary w...