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Principles of Toxicology: Environmental and Industrial Applications / Edition 2

Principles of Toxicology: Environmental and Industrial Applications / Edition 2


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A fully updated and expanded edition of the bestselling guide on toxicology and its practical application

The field of toxicology has grown enormously since Industrial Toxicology: Safety and Health Applications in the Workplace was first published in 1985. And while the original edition was hugely popular among occupational health professionals, the time is ripe to address toxic agents not only in the industrial setting but also in the environment at large. Renamed Principles of Toxicology: Environmental and Industrial Applications, this new edition provides health protection professionals as well as environmental scientists with precise, up-to-date, practical information on how to apply the science of toxicology in both the occupational and environmental setting. Through contributions from leading experts in diverse fields, Principles of Toxicology, Second Edition features:

* Clear explanations of the fundamentals necessary for an understanding of the effects of chemical hazards on human health and ecosystems

* Coverage of occupational medicine and epidemiological issues

* The manifestation of toxic agents such as metals, pesticides, organic solvents, and natural toxins

* Special emphasis on the evaluation and control of toxic hazards

* Specific case histories on applying risk assessment methods in the modern workplace

* Ample figures, references, and a comprehensive glossary of toxicological terms

Product Details

ISBN-13: 9780471293217
Publisher: Wiley
Publication date: 03/28/2000
Edition description: REV
Pages: 624
Product dimensions: 7.22(w) x 10.18(h) x 1.66(d)

About the Author

PHILLIP L. WILLIAMS, PhD, is Associate Professor of Environmental Health Science at the University of Georgia, Athens.

ROBERT C. JAMES, PhD, is President of TERRA, Inc., Tallahassee, Florida, and Associate Scientist at the Center for Environmental and Human Toxicology at the University of Florida, Gainesville.

STEPHEN M. ROBERTS, PhD, is Professor and Program Director of the Center for Environmental and Human Toxicology at the University of Florida, Gainesville.

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Table of Contents


General Principles of Toxicology (R. James, et al.).

Absorption, Distribution, and Elimination of Toxic Agents (E. O'Flaherty).

Biotransformation: A Balance between Bioactivation and Detoxification (M. Franklin & G. Yost).

Hematotoxicity: Chemically Induced Toxicity of the Blood (R. Budinsky).

Hepatotoxicity: Toxic Effects on the Liver (S. Roberts, et al.).

Nephrotoxicity: Toxic Responses of the Kidney (P. Middendorf & P. Williams).

Neurotoxicity: Toxic Responses of the Nervous System (S. Donkin & P. Williams).

Dermal and Ocular Toxicology: Toxic Effects of the Skin and Eyes (W. Salminen & S. Roberts).

Pulmonotoxicity: Toxic Effects in the Lung (C. Dallas).

Immunotoxicity: Toxic Effects on the Immune System (S. Roberts & L. Adams).


Reproductive Toxicology (R. DeMott & C. Borgert).

Mutagenesis and Genetic Toxicology (C. Teaf & P. Middendorf).

Chemical Carcinogenesis (R. James & C. Saranko).

Properties and Effects of Metals (S. Donkin, et al.).

Properties and Effects of Pesticides (J. Britt).

Properties and Effects of Organic Solvents (C. Teaf).

Properties and Effects of Natural Toxins and Venoms (W. Kem).


Risk Assessment (R. James, et al.).

Example of Risk Assessment Applications (A. Nye, et al.).

Occupational and Environmental Health (F. Gerr, et al.).

Epidemiologic Issues in Occupational and Environmental Health (L. Fleming & J. Bean).

Controlling Occupational and Environmental Health Hazards (P. Middendorf & D. Jacobs).



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