Proteolysis in Wound Repair

Extracellular matrix (ECM) turnover is a widespread but in­ completely understood process. Many studies have been con­ ducted with the aim of discovering the general mechanisms which produce and maintain the ECM in tissues. Wound re­ pair in animals has always been a suitable "tool" for exploring these mechanisms. In such a pathologic event, the different components of the healing system can be readily observed since they are exaggerated. It has now become clear that the regulation of prote...