The Hologenome Concept: Human, Animal and Plant Microbiota

Groundbreaking research over the last 10 years has given rise to the hologenome concept of evolution. This concept posits that the holobiont (host plus all of its associated microorganisms) and its hologenome (sum of the genetic information of the host and its symbiotic microorganisms), acting in concert, function as a unique biological entity and therefore as a level of selection in evolution.

All animals and plants harbor abundant and diverse microbiota, including viruses. Often the amount...