The Renin Angiotensin System in the Brain: A Model for the Synthesis of Peptides in the Brain

The first publications on the presence of renin, angiotensino­ gen and angiotensin-like material in brain tissue appeared about ten years ago. This coincided with the discovery of new biological actions of angiotensin in the brain and with the reinvestigation of already known central angiotensin effects. The possibility that angiotensin could be generated within the brain itself had therefore exciting implications. With the recent popularity of brain neuropeptides, interest in this area is ...