Therapeutic Peptides: Methods and Protocols

Therapeutic Peptides: Methods and Protocols

by Andrew E. Nixon (Editor)

Paperback(Softcover reprint of the original 1st ed. 2014)

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Product Details

ISBN-13: 9781493957125
Publisher: Springer-Verlag New York, LLC
Publication date: 08/23/2016
Series: Methods in Molecular Biology , #1088
Edition description: Softcover reprint of the original 1st ed. 2014
Pages: 279
Product dimensions: 7.01(w) x 10.00(h) x 0.02(d)

Table of Contents

1. Design of Phage-Displayed Cystine-Stabilized Mini-Protein Libraries for Proteinaceous Binder Engineering

Hung-Ju Chang and An-Suei Yang

2. Construction of a Filamentous Phage Display Peptide Library

Annette Fagerlund, Astrid Hilde Myrset, and Mari Ann Kulseth

3. Engineering Bio-Active Peptide-Based Therapeutic Molecules

Jong Sang Ryu, A. Yeon Cho, Sang Won Seo, and Hosung Min

4. T7 Lytic Phage-Displayed Peptide Libraries: Construction and Diversity Characterization

Lauren R.H. Krumpe and Toshiyuki Mori

5. Affinity Selection Using Filamentous Phage Display

Mari Ann Kulseth, Annette Fagerlund, and Astrid Hilde Myrset

6. Bioprospecting Open Reading Frames for Peptide Effectors

Ling Xiong and Charles Scott

7. Identification of Ideal Peptides for Heterovalent Ligands

Ajay Shrivastava, Matthew von Wronski, Michael F. Tweedle, and Adrian D. Nunn

8. Substrate Phage Display for Protease Substrate Sequence Characterization: Bovine Factor Xa as a Model System

Hung-Ju Hsu and An-Suei Yang

9. Engineering Peptide Therapeutics Using MIMETIBODY™ Technology

Kristen Picha, Chichi Huang, Peter Bugelski, and Karyn O’Neil

10. Evaluation of Peptides as Protease Inhibitors and Stimulators

Hannu Koistinen, Can Hekim, Ping Wu, Ale Närvänen, and Ulf-Håkan Stenman

11. Assessment of Antimicrobial (Host Defense) Peptides as Anti-Cancer Agents

Susan Douglas, David Hoskin, and Ashley Hilchie

12. Peptide Labelling Strategies for Imaging Agents

Tuulia Huhtala, Janne Weisell, Jussi Rytkönen, and Ale Närvänen

13. Peptide Optimization and Conjugation Strategies in the Development of Molecularly Targeted Magnetic Resonance Imaging Contrast Agents

Andrew F. Kolodziej, Zhaoda Zhang, Kirsten Overoye-Chan, Vincent Jacques, and Peter Caravan

14. Evaluation of Prenylated Peptides for Use in Cellular Imaging and Biochemical Analysis

Joshua D. Ochocki, Urule Igbavboa, W. Gibson Wood, Elizabeth V. Wattenberg, and Mark D. Distefano

15. Ultraviolet Absorption Spectroscopy of Peptides

Mangala R. Liyanage, Kunal Bakshi, David B. Volkin, and C. Russell Middaugh

16. Fluorescence Spectroscopy of Peptides

Mangala R. Liyanage, Kunal Bakshi, David B. Volkin, and C. Russell Middaugh

17. Circular Dichroism of Peptides

Kunal Bakshi, Mangala R. Liyanage, David B. Volkin, and C. Russell Middaugh

18. Fourier Transform Infrared Spectroscopy of Peptides

Kunal Bakshi, Mangala R. Liyanage, David B. Volkin, and C. Russell Middaugh

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