Table of Contents
Section 1: Anxiety Disorders
Chapter 1: Cognitive-Behavioral Therapy, Imipramine, or Their Combination for Panic Disorder
Amanda Sun and Tobias Wasser
Chapter 2: Fluoxetine, Comprehensive Cognitive Behavioral Therapy, and Placebo in Generalized Social Phobia
Erin Habecker and Tobias Wasser
Section 2: Bipolar Disorder
Chapter 3: Lithium Plus Valproate Combination Versus Monotherapy for Relapse Prevention in Bipolar I Disorder (BALANCE)
João Paulo De Aquino and Robert Beech
Chapter 4: Mood Stabilizer Monotherapy vs. Adjunctive Antidepressant for Bipolar Depression: The STEP-BD Trial
João Paulo De Aquino and Robert Beech
Chapter 5: Suicide Risk in Bipolar Disorder: Comparing Lithium, Divalproex, and Carbamazepine
Rachel Katz and Robert Beech
Chapter 6: The Long-term Natural History of Bipolar I Disorder
Zachary Engler and Robert Beech
Section 3: Child and Adolescent Disorders
Chapter 7: The Multimodal Treatment Study of Children with Attention Deficit/Hyperactivity Disorder (MTA)
Michael Hochman, edited by Michael H. Bloch
Chapter 8: Adolescents with SSRI-Resistant Depression: The TORDIA Trial
Amalia Londono Tobon and Hanna Stevens
Chapter 9: Treatment of Early-Onset Schizophrenia Spectrum Disorders (TEOSS) Study
J. Corey Williams and Hanna Stevens
Chapter 10: Cognitive Behavioral Therapy, Sertraline, or a Combination in Childhood Anxiety: CAMS
David Saunders, Jerome Taylor, and Andres Martin
Chapter 11: Predictors of Suicidal Events: The Treatment of Adolescent Suicide Attempters study (TASA)
Michael Maksimowski and Zheala Qayyum
Chapter 12: Cognitive Behavior Therapy, Sertraline, and Their Combination for Children and Adolescents with OCD
Falisha Gilman and Zheala Qayyum
Chapter 13: Initial Treatment of Bipolar I Disorder in Children and Adolescents: The TEAM Trial
Stephanie Ng and Andres Martin
Chapter 14: The Treatment for Adolescents with Depression Study (TADS)
Zachary Engler and Zheala Qayyum
Section 4: Cognitive Disorders: Delirium/Dementia
Chapter 15: Effectiveness of Atypical Antipsychotic Drugs in Patients with Alzheimer's Disease: CATIE-AD
Adam Mecca and Rajesh R. Tampi
Chapter 16: Risk of Death with Atypical Antipsychotic Medications for Dementia
Adam Mecca and Rajesh R. Tampi
Chapter 17: Treatment of Delirium in Hospitalized AIDS Patients: A Double-Blind Trial of Haloperidol, Chlorpromazine, and Lorazepam
Amanda Sun and Rajesh R. Tampi
Chapter 18: Memantine in Patients with Moderate to Severe Alzheimer Disease Already Receiving Donepezil
Brandon M. Kitay and Rajesh R. Tampi
Section 5: Epidemiology
Chapter 19: Global Burden of Mental and Substance Use Disorders
Stephanie Yarnell and Ellen Edens
Chapter 20: Prevalence and Severity of Psychiatric Comorbidities: The National Comorbidity Survey Replication (NCS-R)
Stephanie Yarnell and Ellen Edens
Section 6: Insomnia
Chapter 21: Behavioral and/or Pharmacotherapy for Older Patients with Insomnia
Robert Ross and Rajesh R. Tampi
Section 7: Major Depressive Disorder
Chapter 22: Treatment of Depression in Patients with Alcohol or Drug Dependence: A Meta-Analysis
J. Corey Williams and Gustavo Angarita-Africano
Chapter 23: Suicidality in Pediatric Patients Treated with Antidepressant Drugs: FDA Meta-analysis
David Saunders and Michael H. Bloch
Chapter 24: National Institute of Mental Health (NIMH) Treatment of Depression Collaborative Research Program
Joseph Taylor and Robert Ostroff
Chapter 25: Efficacy and Safety of Electroconvulsive Therapy in Depressive Disorders: A Systematic Review and Meta-analysis
Joseph Taylor and Robert Ostroff
Chapter 26: Initial Severity and Antidepressant Benefits: A Meta-Analysis of Data Submitted to the Food and Drug Administration
Michael Maksimowski and Zheala Qayyum
Chapter 27: Sequenced Treatment Alternatives to Relieve Depression: STAR*D
Eric Lin and Pochu Ho
Chapter 28: Cognitive Therapy vs. Medication in the Treatment of Moderate to Severe Depression
Daniel Barron and Robert Ostroff
Section 8: Obsessive Compulsive Disorder
Chapter 29: Exposure and Ritual Prevention, Clomipramine, or Their Combination for Obsessive-Compulsive Disorder
Brandon M. Kitay and Michael H. Bloch
Chapter 30: Meta-analysis of the Dose-response relationship of SSRI's in adult patients with Obsessive Compulsive Disorder
Eunice Yuen and Michael H. Bloch
Section 9: Personality Disorders
Chapter 31: Psychotherapy for Borderline Personality Disorder: A Multiwave Study
David Grunwald, Erica Robinson, and Sarah Fineberg
Chapter 32: Dialectical Behavior Therapy vs. Community Treatment by Experts for Reducing Suicidal Behaviors Among Patients with Borderline Personality Disorder
David Saunders, Erica Robinson, and Sarah Fineberg
Chapter 33: Ten-Year Course of Borderline Personality Disorder: The Collaborative Longitudinal Personality Disorders Study
Kevin Johnson, Erica Robinson, and Sarah Fineberg
Section 10: Psychiatry in Primary Care
Chapter 34: Depressive Symptoms and Health-Related Quality of Life: The Heart and Soul Study
Amalia Londono Tobon and Catherine Chiles
Chapter 35: The Canadian Cardiac Randomized Evaluation of Antidepressant and Psychotherapy Efficacy (CREATE) Trial
Nikhil Gupta and Catherine Chiles
Section 11: Women's Mental Health
Chapter 36: Buprenorphine vs. Methadone During Pregnancy: The MOTHER Trial
Rachel Wurmser and Kirstin Wilkins
Section 12: Schizophrenia
Chapter 37: QTc-Interval Abnormalities and Psychotropic Drug Therapy in Psychiatric Patients
Amanda Sun and Vinod H. Srihari
Chapter 38: Tardive Dyskinesia with Atypical vs. Conventional Antipsychotic Medications
Emma Lo and Cenk Tek
Chapter 39: Effectiveness of Antipsychotics in the Treatment of Schizophrenia: CATIE Phase 1
Chadrick Lane and Mohini Ranganathan
Chapter 40: Clozapine for Treatment-Resistant Schizophrenia
Chadrick Lane and Vinod H. Srihari
Chapter 41: Effectiveness of clozapine vs. other atypical antipsychotics: Clinical Antipsychotic Trials for Interventions Effectiveness (CATIE)
Eunice Yuen and Cenk Tek
Chapter 42: Atypical Antipsychotic Drugs and the Risk of Sudden Cardiac Death
Hamilton Hicks and Cenk Tek
Chapter 43: Switching Antipsychotics to Reduce Metabolic Risk: The CAMP Trial
Eric Lin and John Cahill
Chapter 44: Cost Utility of Atypical Antipsychotics: CUtLASS-1
Nikhil Gupta and John Cahill
Chapter 45: North American Prodrome Longitudinal Study
Nikhil Gupta and Vinod H. Srihari
Chapter 46: Clozapine for Suicidality in Schizophrenia: The International Suicide Prevention Trial (InterSePT)
Daniel Barron and Noah Capurso
Chapter 47: A Cohort Study of Oral and Depot Antipsychotics After First Hospitalization for Schizophrenia
Stephanie Ng and Cenk Tek
Section 13: Substance Use Disorders
Chapter 48: Methadone Maintenance vs. Detoxification and Psychosocial Treatment for Opioid Dependence: The M180 Study
Hamilton Hicks and Srinivas Muvvala
Chapter 49: Combined Pharmacotherapies and Behavioral Interventions for Alcohol Dependence: The COMBINE Study
Kevin Johnson and Srinivas Muvvala
Chapter 50: Levomethadyl acetate vs. Buprenorphine vs. Methadone for Opioid Dependence
Robert Ross and Brian Fuehrlein