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A “comic extravaganza” (Washington Post Book World) from one of the most acclaimed voices in American avant-garde literature, Tlooth follows its narrator on a fantastical, globe-trotting quest for revenge.

Opening on a baseball game in a Siberian prison camp, Harry Mathews’s Tlooth is absurdist from the jump. The narrator, a three-fingered dental assistant who escapes from Russia to find the criminal surgeon who took the other two fingers, treks across half the world—from Kabul to Venice to...