Bacterial Artificial Chromosomes

This book gives emphasis to the various applications of Bacterial Artificial Chromosomes (BACs) in various studies. The topics presented are - using BAC libraries as assets for the mapping of marsupial and monotreme gene and for comparative genomic studies, and the usage of BACs as vehicles for maintaining the large infectious DNA genomes of viruses. The huge size of the insert DNA in the BACs and the ease with which engineering mutations in that DNA within the bacterial host can be achieve...