ISBN-10:
1441922911
ISBN-13:
9781441922915
Pub. Date:
11/25/2010
Publisher:
Springer New York
Cell Stress Proteins / Edition 1

Cell Stress Proteins / Edition 1

by Stuart K. Calderwood

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Product Details

ISBN-13: 9781441922915
Publisher: Springer New York
Publication date: 11/25/2010
Series: Protein Reviews , #7
Edition description: Softcover reprint of hardcover 1st ed. 2007
Pages: 460
Product dimensions: 6.10(w) x 9.25(h) x 0.24(d)

Table of Contents

Introduction: Heat Shock Proteins—From Drosophila Stress Proteins to Mediators of Human Disease.- Introduction: Heat Shock Proteins—From Drosophila Stress Proteins to Mediators of Human Disease.- Stress Response and Molecular Chaperones.- Biology of the Heat Shock Response and Stress Conditioning.- Bacterial Stress Sensors.- Unfolded Protein Response: Contributions to Development and Disease.- Molecular Mechanisms of Stress Protein Expression.- Genetic Models of HSF Function.- HSF1 and HSP Gene Regulation.- Cellular Stress Proteins.- Small Heat Shock Proteins in Physiological and Stress-Related Processes.- Large Mammalian hsp70 Family Proteins, hsp110 and grp170, and Their Roles in Biology and Cancer Therapy.- Molecular Chaperones and Protein Folding.- Regulation of Hsp70 Function: Hsp40 Co-Chaperones and Nucleotide Exchange Factors.- Protein Disassembly by Hsp40-Hsp70.- Mammalian HSP40/DnaJ Chaperone Proteins in Cytosol.- Role of Molecular Chaperones in Cell Regulation.- FKBP Co-Chaperones in Steroid Receptor Complexes.- Up and Down Regulation of the Stress Response by the Co-Chaperone Ubiquitin Ligase CHIP.- Role of Cdc37 in Protein Kinase Folding.- Intracellular and Extracellular Stress Proteins in Human Disease.- Targeting Hsp90 in Cancer and Neurodegenerative Disease.- gp96 and Tumor Immunity.- Immunoregulatory Activities of Extracellular Stress Proteins.- Heat Shock Proteins and Neurodegenerative Diseases.- Heat Shock Proteins in the Progression of Cancer.

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