Concepts and Applications of Single-Cell Analysis

Single-cell analysis (SCA) refers to the study of metabolomics, transcriptomics, cell-cell interactions, genomics and proteomics at the single cell level. Various SCA techniques require isolation of individual cells. Currently, several methods are utilized for single cell isolation, such as laser capture microdissection, serial dilution, FACS, micromanipulation, dielectrophoretic digital sorting, and Raman tweezers. Laser capture microdissection involves the isolation of specific cells by p...