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Design and Analysis of Clinical Trials for Predictive Medicine

By Shigeyuki Matsui (Editor), Marc Buyse (Editor), Richard Simon (Editor)
Hardcover
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By Shigeyuki Matsui (Editor), Marc Buyse (Editor), Richard Simon (Editor)
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Design and Analysis of Clinical Trials for Predictive Medicine provides statistical guidance on conducting clinical trials for predictive medicine. It covers statistical topics relevant to the main clinical research phases for developing molecular diagnostics and therapeutics—from identifying molecular biomarkers using DNA microarrays to confirming their clinical utility in randomized clinical trials.

The foundation of modern clinical trials was laid many years before modern developments in...

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Science & TechnologyMathematicsProbability TheoryStatistics