DNA-Encoded Chemical Libraries: Methods and Protocols
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This volume discusses prools that cover synthesis, screening by selection, and analysis of DNAencoded chemical libraries (DEL). Chapters in this book focus on methods used to practice DEL technology and include solution phase library synthesis using a variety of chemistries; DNA encoding of chemical structure; design, preparation and analysis of target proteins and tool compounds; screening of soluble protein targets by affinity selection; DEL qPCR, preparative PCR and DNA sequence analysi...






















