Hepatic Transport of Organic Substances

Hepatic cells are involved in the metabolization and elimination of a variety of endogenous and exogenous substances. They mediate the uptake, processing and subsequent secretion of biliary compounds, such as various drugs or hormones, and the passage of metabolites to be released into different blood compartments. To perform vectorial passages hepaytes show a strong polarity with sites for endocytotic processes or specific carrier molecules, and a specified system of organelles for intrace...